There are 4 ways to get from Amarillo to San Antonio by plane, bus or car

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Amarillo to San Antonio by bus

The bus journey time between Amarillo and San Antonio is around 11h 25m and covers a distance of around 559 miles. The fastest bus normally takes 11h 25m. Services are operated by Greyhound USA. Typically seven buses run weekly, although weekend and holiday schedules can vary so check in advance.

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The schedules shown below are for the next available departures.

Amarillo to San Antonio bus schedules


Greyhound USA
Greyhound USA
Greyhound USA
Greyhound USA
Greyhound USA

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If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636


Domestic travel is not restricted, but some conditions may applyFace masks are recommendedThere is a social distancing requirement of 2 metresDomestic border crossings may be subject to approval, testing and quarantine

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Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.


Last updated: 13 Oct 2021 Exceptions may apply, for full details: Centers for Disease control and prevention (CDC). We"re working around the clock to bring you the latest COVID-19 travel updates.This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.Visit mmsanotherstage2019.com travel advice for general help.


The cheapest way to get from Amarillo to San Antonio is to drive which costs $50-$75 and takes 9h 12m.

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The fastest way to get from Amarillo to San Antonio is to fly which takes 4h 43m and costs $130-$360.

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Yes, there is a direct bus departing from Amarillo and arriving at San Antonio. Services depart once daily, and operate every day. The journey takes approximately 11h 25m.

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The distance between Amarillo and San Antonio is 448 miles. The road distance is 512.8 miles.

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The best way to get from Amarillo to San Antonio without a car is to bus which takes 11h 25m and costs $55-$85.

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It takes approximately 4h 43m to get from Amarillo to San Antonio, including transfers.

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Amarillo to San Antonio bus services, operated by Greyhound USA, depart from Amarillo station.

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The best way to get from Amarillo to San Antonio is to fly which takes 4h 43m and costs $130-$360. Alternatively, you can bus, which costs $55-$85 and takes 11h 25m.

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There is no direct flight from Amarillo Airport to San Antonio Airport. The quickest flight takes 3h 24m and has one stopover.

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Amarillo to San Antonio bus services, operated by Greyhound USA, arrive at San Antonio station.

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Website allegiantair.com Flights from Amarillo to Austin Ave. Duration 1h 25m When Thursday Estimated price $40-$230

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